Services

Protein Analytics

  • Protein activity
    • Binding affinity
    • Enzyme activity
    • Cell-based assays
    • In vivo testing
  • Protein stability
    • Tm & Tagg
    • ΔG
    • Isothermal stability
    • Thermal recovery
    • Sizing & polydispersity
    • Sizing with thermal ramp
    • B22 & kD
    • Viscosity
  • Protein titer/concentration
    • Protein A HPLC
    • ELISA
    • A280
  • Protein integrity and structure
    • Size variants by SEC-HPLC
    • Size variants by SEC-MALS
    • Size variants by CE-SDS (reduced and non-reduced)
    • Hydrophobic variants by RP-HPLC/UPLC or HIC
    • Protein purity by SDS-PAGE
    • N-glycan analysis by HILIC-FLD
    • N-glycan analysis by CE
    • Sialic acid content by DMB RP
    • Free thiol content by SEC-FLD
    • Charge variants by cIEF
    • Western Blot
    • HCP titer by ELISA
    • Residual Protein A, Protein G, Protein L by ELISA or Octet
    • Endotoxin levels by LAL
  • Protein mass (Agilent HPLC-CHIP/QTOF)
    • Accurate mass: proteins, protein-drug conjugates
    • Peptide and Glycan mapping
    • Determination of post-translations modifications either in known or unknown samples.
    • Standard COAs
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